How cancer-fighting immune cells could be made safer and more powerful
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How cancer-fighting immune cells could be made safer and more powerful

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A CAR T-cell (yellow) and a brain cancer cell (pink) viewed with an electron microscope

STEVE GSCHMEISSNER/SCIENCE PHOTO LIBRARY

An improved way of engineering immune cells to fight cancers and other conditions could make them safer and more effective. It would also allow doctors to pause the treatment if someone had severe side effects.

“It could give an extra level of control over the systems,” says Jason Lohmueller at the University of Pittsburgh, Pennsylvania. “We’re excited about the additional safety.”

CAR T-cells are immune cells that are genetically engineered to attack specific targets in …

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